What is a common symptom of organophosphate poisoning?

Lacrimation, or excessive tear production, is a hallmark symptom of organophosphate poisoning due to the inhibition of the enzyme acetylcholinesterase. This inhibition leads to an accumulation of acetylcholine in synapses, resulting in overstimulation of acetylcholine receptors. The overstimulation of these receptors in the parasympathetic nervous system causes a variety of symptoms, including increased secretions such as tears, saliva, and mucus.

In the context of organophosphate exposure, lacrimation can be seen alongside other cholinergic symptoms, such as salivation, urination, defecation, gastrointestinal distress, and muscle twitching. Recognizing lacrimation as a symptom helps in diagnosing and managing organophosphate poisoning, emphasizing the importance of monitoring for this sign in potentially exposed patients.