What physiological change does Cushing's Reflex indicate?

Cushing's Reflex is a physiological response observed in cases of increased intracranial pressure (ICP). When intracranial pressure rises significantly, it can lead to a dangerous condition where the brain is unable to receive adequate perfusion. The body responds to this crisis through a series of changes, specifically in an attempt to maintain blood flow to vital organs, particularly the brain.

As ICP increases, the body initiates a compensatory mechanism to restore cerebral perfusion pressure. This includes a significant rise in blood pressure. The resulting effects of Cushing's Reflex can include bradycardia (a decreased heart rate) and hypertension (increased blood pressure), hence manifesting as a bradycardic response paired with elevated systemic vascular resistance.

In recognizing Cushing's Reflex, increased intracranial pressure is identified as the primary physiological change initiating these adaptations. Understanding this reflex is crucial for evaluating and managing patients with potential brain injury or significant trauma.