Which organ is responsible for the filtration of drugs and poisonous substances from the blood?

The liver is primarily responsible for the filtration and metabolism of drugs and poisonous substances from the blood. This vital organ processes various compounds through a series of enzymatic reactions, which can either detoxify substances or convert them into forms that can be more easily excreted by the body. The liver plays a crucial role in drug metabolism, where it transforms lipophilic compounds into hydrophilic metabolites that can then be excreted via urine or bile.

While the kidneys also play a significant role in filtering waste products and excreting toxins, their function is more focused on maintaining homeostasis by regulating fluid balance and electrolytes, rather than actively metabolizing substances. The spleen is involved in filtering blood and managing immune responses, and the pancreas primarily deals with digestive enzymes and hormones related to glucose metabolism. Each organ has distinct functions, but the liver's central role in drug metabolism and detoxification highlights its significance in the body's ability to process potentially harmful substances.