Which route of medication absorption involves administration into the bone?

The intraosseous route of medication absorption specifically involves administering medications directly into the bone marrow. This method is particularly useful in emergency situations where intravenous access is difficult or time-consuming, allowing for rapid absorption of medications directly into the bloodstream.

When medications are delivered via the intraosseous route, the rich vascular supply within the bone marrow facilitates quick systemic delivery. This route is especially common in pediatric patients or in critical situations where intravenous access is challenging. Using the intraosseous route can be life-saving due to its quick onset of action when immediate treatment is essential.

In contrast, intradermal administration involves injecting medication into the dermal layer of the skin, which is primarily used for allergy testing or vaccinations. Intranasal delivery administers medications through the nasal mucosa, taking advantage of the rich blood supply in that area to facilitate rapid absorption, but not by accessing the bone. Intramuscular administration involves injecting medication into muscle tissue, which is also effective but does not provide the rapid access to the central circulation that intraosseous delivery can.